Long COVID Beyond the Acute Phase: Inflammation, Hypoxia, and Redundant Pathways Driving Chronic Disease

Graham Exelby
15 hours ago
1 min read

Author: Dr Graham Exelby, revised by Dr Valerio Vittone (PhD)

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Upright Head Pressure in Long COVID- from Acute Neurovascular Injury to Chronic Hypoxic Support Failure- a Mechanistic Hypothesis

Dr Graham Exelby, Ms Michelle Hill

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Dr Graham Exelby. November 2025 Abstract Background: Recent mechanistic work proposes preload failure as the initiating lesion in POTS and Long COVID, linking orthostatic intolerance to mechanical, va

Reframing Postural Orthostatic Tachycardia Syndrome (POTS) as a Disorder of Preload Failure: Integrating Neurovascular and Immune Pathways

Dr Graham Exelby October 2025 Abstract Background: Postural Orthostatic Tachycardia Syndrome (POTS) is a multisystem disorder of orthostatic intolerance characterised by excessive heart-rate increment

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