

Lymphatic Obstruction in POTS, CFS, and Long COVID: A Call for Integrated Therapeutic Approaches
- Unblocking the Invisible Network: Fascia, Mast Cells, and the Clinical Relevance of Lymphatic Obstruction in Complex Syndromes Dr...
Graham Exelby
16 min read


Mould, Sustained Stress, and PTSD Converge on the RAGE–TLR4 Axis: A Unifying Model of Neuroimmune Dysregulation
Dr Graham Exelby May 2025 Abstract Chronic mould exposure, sustained psychological stress, and PTSD have emerged as key environmental...
Graham Exelby
40 min read
Locus Coeruleus Hypoperfusion and Noradrenergic Vasospasm: A Central Mechanism in Dysautonomia and Cerebral Hypoperfusion
Dr Graham Exelby May 2025 Abstract Brainstem hypoperfusion is increasingly recognized as a unifying feature in dysautonomic syndromes...
Graham Exelby
17 min read
Hydraulic and Vascular Autonomic Dysregulation in POTS- The Modified Geddes Baroreceptor Hypothesis
Dr Graham Exelby May 2025 Abstract Postural Orthostatic Tachycardia Syndrome (POTS) reflects a multifactorial disruption of vascular,...
Graham Exelby
10 min read


Dysautonomia as a Neuroimmune–Metabolic Disorder: A Unified Model Linking TLR4 Activation, Brainstem Hypoxia, and Autonomic Plexus Dysfunction
Dr Graham Exelby May 2025 Contents: 1. Abstract 2. Introduction 3. Section 1- Linking Immune dysregulation to Metabolic,...
Graham Exelby
30 min read
Heat and Cold Intolerance
Dr Graham Exelby December 2024 Temperature intolerance is a common symptom in Postural Orthostatic Tachycardia Syndrome (POTS) and often...
Graham Exelby
4 min read


The Glymphatic System
Glymphatic System (or glymphatic clearance pathway or paravascular system) Dr Graham Exelby. January 2024- Currently under revision...
Graham Exelby
33 min read


DNA Mutations in POTS and Long Covid-Practitioner version MCAS Conference- April 2 2023-
By Dr Valerio Vittone Screendumps from Dr Vittone's presentation at the MCAS Conference April 2023
Graham Exelby
1 min read


Nigella Sativa in COVID
Black seed or N. sativa that belongs to the Ranunculacea family has a rich historical and religious background. It is native to southwest...
Graham Exelby
13 min read


Nicotinamide Mononucleotide (NMN)
Dr Graham Exelby May 2024 Currently being revised to incorporate the use of nicotinamide in amino acid dysfunction Nicotinamide...
Graham Exelby
8 min read
Low Dose Naltrexone, Ketotifen and other Mast Cell Treatments
Dr Graham Exelby May 2024 This is part of a personal management protocol in POTS, Long Covid and other MCAS-associated conditions. There...
Graham Exelby
12 min read




























