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Mermaid Central Medical Clinic Research

Sharing research in Long COVID, POTS, fibromyalgia and other areas

Mould, Sustained Stress, and PTSD Converge on the RAGE–TLR4 Axis: A Unifying Model of Neuroimmune Dysregulation

Mould, Sustained Stress, and PTSD Converge on the RAGE–TLR4 Axis: A Unifying Model of Neuroimmune Dysregulation

Mould, Sustained Stress, and PTSD Converge on the RAGE–TLR4 Axis: A Unifying Model of Neuroimmune Dysregulation

Dr Graham Exelby May 2025 Abstract Chronic mould exposure, sustained psychological stress, and PTSD have emerged as key environmental...

Graham Exelby

40 min read

Hydraulic and Vascular Autonomic Dysregulation in POTS- The Modified Geddes Baroreceptor Hypothesis

Dr Graham Exelby May 2025 Abstract Postural Orthostatic Tachycardia Syndrome (POTS) reflects a multifactorial disruption of vascular,...

Graham Exelby

10 min read

Dysautonomia as a Neuroimmune–Metabolic Disorder: A Unified Model Linking TLR4 Activation, Brainstem Hypoxia, and Autonomic Plexus Dysfunction

Dysautonomia as a Neuroimmune–Metabolic Disorder: A Unified Model Linking TLR4 Activation, Brainstem Hypoxia, and Autonomic Plexus Dysfunction

Dysautonomia as a Neuroimmune–Metabolic Disorder: A Unified Model Linking TLR4 Activation, Brainstem Hypoxia, and Autonomic Plexus Dysfunction

Dr Graham Exelby May 2025 Contents: 1. Abstract 2. Introduction 3. Section 1- Linking Immune dysregulation to Metabolic,...

Graham Exelby

30 min read

Articles Categories

Articles List

Neuro-Immune–Hydraulic Integrative Phenotype Axis (NIHPA): The Conceptual Framework where One Core Engine drives Multiple Phenotypic Variants

Genomic Redundancy as a Driver of Chronicity in POTS and Long COVID: a Preliminary Study of Convergent Pathway Disruption

Epstein–Barr Virus Reactivation in Long COVID: A Clinical Overview for Physicians

What DNA Can Teach Us in Understanding POTS, ME/CFS, and Long COVID

Tilt Testing in POTS : Safe and Effective Options

Ascending Aortic Dilatation in Athletes with Thoracic Outlet Syndrome and the Therapeutic Role of Telmisartan

Azygous Vein Dysfunction in POTS

The Systemic Consequences of STAT3 Dysregulation in Long COVID:

POTS Comorbidities- by Functional Domain

RAGE: A Central Amplifier in POTS

Lymphatic Obstruction in POTS, CFS, and Long COVID: A Call for Integrated Therapeutic Approaches

Mould, Sustained Stress, and PTSD Converge on the RAGE–TLR4 Axis: A Unifying Model of Neuroimmune Dysregulation

Locus Coeruleus Hypoperfusion and Noradrenergic Vasospasm: A Central Mechanism in Dysautonomia and Cerebral Hypoperfusion

Hydraulic and Vascular Autonomic Dysregulation in POTS- The Modified Geddes Baroreceptor Hypothesis

Dysautonomia as a Neuroimmune–Metabolic Disorder: A Unified Model Linking TLR4 Activation, Brainstem Hypoxia, and Autonomic Plexus Dysfunction

Coeliac Plexus in POTS : Insights into MALS, SMA and Nutcracker Syndrome in POTS

Cardiac Plexus in POTS- a Central Node in POTS Pathophysiology

Autonomic Dysregulation: A Systems-Level Integration of Brainstem Hypoperfusion, Plexus Dysfunction, and Immune-Metabolic Crosstalk in Dysautonomia

Heart Rate Variability (HRV) in Autonomic Assessment

Thoracic Outlet Syndrome, Abdominal Vascular Compression Syndromes and the Functional Continuum in Dysautonomia

RAGE–TLR4–NF-κB–CCL2 Looping Activation in Long COVID and Sensitization Syndromes

QT Prolongation in COVID and Long COVID

Integrated Immune and Metabolic Dysfunction in POTS and Long COVID

Hypoxia-Driven RAGE Activation: A Core Pathophysiology

Heat and Cold Intolerance

The Genetic Basis to Improving Toxin Detoxification

Intra-Abdominal Vascular Compression Syndromes

The Glymphatic System

DNA Mutations in POTS and Long Covid-Practitioner version MCAS Conference- April 2 2023-

Nigella Sativa in COVID

Nicotinamide Mononucleotide (NMN)

Low Dose Naltrexone, Ketotifen and other Mast Cell Treatments

Thoracic Outlet Syndrome (incorporating Costoclavicular Syndrome)

A 50 Year Journey in Medicine

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