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Long COVID
Research in COVID-19 has answered many of the questions that kept popping up in POTS, Fibromyalgia and similar conditions- how a virus (or trauma, mould, parasites, sustained stress) can activate threat receptors (Toll-like receptors, or TLRs) which then activate Mast Cells that are responsible for the cytokine storm that is what happens in COVID.
Lymphatic Obstruction in POTS, CFS, and Long COVID: A Call for Integrated Therapeutic Approaches
- Unblocking the Invisible Network: Fascia, Mast Cells, and the Clinical Relevance of Lymphatic Obstruction in Complex Syndromes Dr...
Graham Exelby
May 25, 2025
Mould, Sustained Stress, and PTSD Converge on the RAGE–TLR4 Axis: A Unifying Model of Neuroimmune Dysregulation
Dr Graham Exelby May 2025 Abstract Chronic mould exposure, sustained psychological stress, and PTSD have emerged as key environmental...
Graham Exelby
May 24, 2025
Locus Coeruleus Hypoperfusion and Noradrenergic Vasospasm: A Central Mechanism in Dysautonomia and Cerebral Hypoperfusion
Dr Graham Exelby May 2025 Abstract Brainstem hypoperfusion is increasingly recognized as a unifying feature in dysautonomic syndromes...
Graham Exelby
May 24, 2025
Hydraulic and Vascular Autonomic Dysregulation in POTS- The Modified Geddes Baroreceptor Hypothesis
Dr Graham Exelby May 2025 Abstract Postural Orthostatic Tachycardia Syndrome (POTS) reflects a multifactorial disruption of vascular,...
Graham Exelby
May 24, 2025
Dysautonomia as a Neuroimmune–Metabolic Disorder: A Unified Model Linking TLR4 Activation, Brainstem Hypoxia, and Autonomic Plexus Dysfunction
Dr Graham Exelby May 2025 Contents: 1. Abstract 2. Introduction 3. Section 1- Linking Immune dysregulation to Metabolic,...
Graham Exelby
May 24, 2025
Heat and Cold Intolerance
Dr Graham Exelby December 2024 Temperature intolerance is a common symptom in Postural Orthostatic Tachycardia Syndrome (POTS) and often...
Graham Exelby
Dec 15, 2024
The Glymphatic System
Glymphatic System (or glymphatic clearance pathway or paravascular system) Dr Graham Exelby. January 2024- Currently under revision...
Graham Exelby
Dec 30, 2023
DNA Mutations in POTS and Long Covid-Practitioner version MCAS Conference- April 2 2023-
By Dr Valerio Vittone Screendumps from Dr Vittone's presentation at the MCAS Conference April 2023
Graham Exelby
Apr 11, 2023
Nigella Sativa in COVID
Black seed or N. sativa that belongs to the Ranunculacea family has a rich historical and religious background. It is native to southwest...
Graham Exelby
Mar 1, 2023
Nicotinamide Mononucleotide (NMN)
Dr Graham Exelby May 2024 Currently being revised to incorporate the use of nicotinamide in amino acid dysfunction Nicotinamide...
Graham Exelby
Dec 30, 2022
Low Dose Naltrexone, Ketotifen and other Mast Cell Treatments
Dr Graham Exelby May 2024 This is part of a personal management protocol in POTS, Long Covid and other MCAS-associated conditions. There...
Graham Exelby
Oct 17, 2022
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